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First total synthesis of ampullosine, a unique isoquinoline alkaloid isolated from Sepedonium ampullosporum, and of the related permethylampullosine

A straightforward and convenient approach toward the first total synthesis of ampullosine, a structurally unique 3-methylisoquinoline alkaloid isolated from Sepedonium ampullosporum, is reported. Access to the related O-methyl ampullosine methyl ester from a common intermediate is also disclosed. Th...

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Detalles Bibliográficos
Autores principales: Vargas, Didier F., Larghi, Enrique L., Kaufman, Teodoro S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073199/
https://www.ncbi.nlm.nih.gov/pubmed/35529133
http://dx.doi.org/10.1039/c9ra06839b

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