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Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths
BACKGROUND: This study aimed to describe the clinical characteristics of maternal deaths associated with COVID-19 registered in a collaborative Latin-American multi-country database. METHODS: This was an observational study implemented from March 1st 2020 to November 29th 2021 in eight Latin America...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073212/ https://www.ncbi.nlm.nih.gov/pubmed/35539820 http://dx.doi.org/10.1016/j.lana.2022.100269 |
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author | Maza-Arnedo, Fabian Paternina-Caicedo, Angel Sosa, Claudio G. de Mucio, Bremen Rojas-Suarez, José Say, Lale Cresswell, Jenny A. de Francisco, Luis Andrés Serruya, Suzanne Lic, Diana Carolina Franco Pulido Urbina, Luis Hilaire, Erika Saint Munayco, César V. Gil, Fabiola Rousselin, Erick Contreras, Leonardo Stefan, Allan Becerra, Alvinzy Velásquez Degraff, Evelyn Espada, Franco Conde, Victor Mery, Gustavo Castaño, Víctor Hugo Álvarez Umbarila, Aura Liliana Torres Romero, Ivy Lorena Talavera Alfonso, Yeimy Catherine Rodríguez Lovato Silva, Raquel Calle, Jakeline Díaz -Viscensini, Cynthia Marlene Frutos, Vicente Nicolas Bataglia Laguardia, Elodia Vysokolán Padilla, Haydee Ciganda, Alvaro Colomar, Mercedes |
author_facet | Maza-Arnedo, Fabian Paternina-Caicedo, Angel Sosa, Claudio G. de Mucio, Bremen Rojas-Suarez, José Say, Lale Cresswell, Jenny A. de Francisco, Luis Andrés Serruya, Suzanne Lic, Diana Carolina Franco Pulido Urbina, Luis Hilaire, Erika Saint Munayco, César V. Gil, Fabiola Rousselin, Erick Contreras, Leonardo Stefan, Allan Becerra, Alvinzy Velásquez Degraff, Evelyn Espada, Franco Conde, Victor Mery, Gustavo Castaño, Víctor Hugo Álvarez Umbarila, Aura Liliana Torres Romero, Ivy Lorena Talavera Alfonso, Yeimy Catherine Rodríguez Lovato Silva, Raquel Calle, Jakeline Díaz -Viscensini, Cynthia Marlene Frutos, Vicente Nicolas Bataglia Laguardia, Elodia Vysokolán Padilla, Haydee Ciganda, Alvaro Colomar, Mercedes |
author_sort | Maza-Arnedo, Fabian |
collection | PubMed |
description | BACKGROUND: This study aimed to describe the clinical characteristics of maternal deaths associated with COVID-19 registered in a collaborative Latin-American multi-country database. METHODS: This was an observational study implemented from March 1st 2020 to November 29th 2021 in eight Latin American countries. Information was based on the Perinatal Information System from the Latin American Center for Perinatology, Women and Reproductive Health. We summarized categorical variables as frequencies and percentages and continuous variables into median with interquartile ranges. FINDINGS: We identified a total of 447 deaths. The median maternal age was 31 years. 86·4% of women were infected antepartum, with most of the cases (60·3%) detected in the third trimester of pregnancy. The most frequent symptoms at first consultation and admission were dyspnea (73·0%), fever (69·0%), and cough (59·0%). Organ dysfunction was reported in 90·4% of women during admission. A total of 64·8% women were admitted to critical care for a median length of eight days. In most cases, the death occurred during the puerperium, with a median of seven days between delivery and death. Preterm delivery was the most common perinatal complication (76·9%) and 59·9% were low birth weight. INTERPRETATION: This study describes the characteristics of maternal deaths in a comprehensive multi-country database in Latin America during the COVID-19 pandemic. Barriers faced by Latin American pregnant women to access intensive care services when required were also revealed. Decision-makers should strengthen severity awareness, and referral strategies to avoid potential delays. FUNDING: Latin American Center for Perinatology, Women and Reproductive Health. |
format | Online Article Text |
id | pubmed-9073212 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-90732122022-05-06 Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths Maza-Arnedo, Fabian Paternina-Caicedo, Angel Sosa, Claudio G. de Mucio, Bremen Rojas-Suarez, José Say, Lale Cresswell, Jenny A. de Francisco, Luis Andrés Serruya, Suzanne Lic, Diana Carolina Franco Pulido Urbina, Luis Hilaire, Erika Saint Munayco, César V. Gil, Fabiola Rousselin, Erick Contreras, Leonardo Stefan, Allan Becerra, Alvinzy Velásquez Degraff, Evelyn Espada, Franco Conde, Victor Mery, Gustavo Castaño, Víctor Hugo Álvarez Umbarila, Aura Liliana Torres Romero, Ivy Lorena Talavera Alfonso, Yeimy Catherine Rodríguez Lovato Silva, Raquel Calle, Jakeline Díaz -Viscensini, Cynthia Marlene Frutos, Vicente Nicolas Bataglia Laguardia, Elodia Vysokolán Padilla, Haydee Ciganda, Alvaro Colomar, Mercedes Lancet Reg Health Am Articles BACKGROUND: This study aimed to describe the clinical characteristics of maternal deaths associated with COVID-19 registered in a collaborative Latin-American multi-country database. METHODS: This was an observational study implemented from March 1st 2020 to November 29th 2021 in eight Latin American countries. Information was based on the Perinatal Information System from the Latin American Center for Perinatology, Women and Reproductive Health. We summarized categorical variables as frequencies and percentages and continuous variables into median with interquartile ranges. FINDINGS: We identified a total of 447 deaths. The median maternal age was 31 years. 86·4% of women were infected antepartum, with most of the cases (60·3%) detected in the third trimester of pregnancy. The most frequent symptoms at first consultation and admission were dyspnea (73·0%), fever (69·0%), and cough (59·0%). Organ dysfunction was reported in 90·4% of women during admission. A total of 64·8% women were admitted to critical care for a median length of eight days. In most cases, the death occurred during the puerperium, with a median of seven days between delivery and death. Preterm delivery was the most common perinatal complication (76·9%) and 59·9% were low birth weight. INTERPRETATION: This study describes the characteristics of maternal deaths in a comprehensive multi-country database in Latin America during the COVID-19 pandemic. Barriers faced by Latin American pregnant women to access intensive care services when required were also revealed. Decision-makers should strengthen severity awareness, and referral strategies to avoid potential delays. FUNDING: Latin American Center for Perinatology, Women and Reproductive Health. Elsevier 2022-05-06 /pmc/articles/PMC9073212/ /pubmed/35539820 http://dx.doi.org/10.1016/j.lana.2022.100269 Text en © 2022 Pan American Health Organization https://creativecommons.org/licenses/by/3.0/igo/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/igo/). |
spellingShingle | Articles Maza-Arnedo, Fabian Paternina-Caicedo, Angel Sosa, Claudio G. de Mucio, Bremen Rojas-Suarez, José Say, Lale Cresswell, Jenny A. de Francisco, Luis Andrés Serruya, Suzanne Lic, Diana Carolina Franco Pulido Urbina, Luis Hilaire, Erika Saint Munayco, César V. Gil, Fabiola Rousselin, Erick Contreras, Leonardo Stefan, Allan Becerra, Alvinzy Velásquez Degraff, Evelyn Espada, Franco Conde, Victor Mery, Gustavo Castaño, Víctor Hugo Álvarez Umbarila, Aura Liliana Torres Romero, Ivy Lorena Talavera Alfonso, Yeimy Catherine Rodríguez Lovato Silva, Raquel Calle, Jakeline Díaz -Viscensini, Cynthia Marlene Frutos, Vicente Nicolas Bataglia Laguardia, Elodia Vysokolán Padilla, Haydee Ciganda, Alvaro Colomar, Mercedes Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths |
title | Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths |
title_full | Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths |
title_fullStr | Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths |
title_full_unstemmed | Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths |
title_short | Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths |
title_sort | maternal mortality linked to covid-19 in latin america: results from a multi-country collaborative database of 447 deaths |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073212/ https://www.ncbi.nlm.nih.gov/pubmed/35539820 http://dx.doi.org/10.1016/j.lana.2022.100269 |
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