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Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths

BACKGROUND: This study aimed to describe the clinical characteristics of maternal deaths associated with COVID-19 registered in a collaborative Latin-American multi-country database. METHODS: This was an observational study implemented from March 1st 2020 to November 29th 2021 in eight Latin America...

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Autores principales: Maza-Arnedo, Fabian, Paternina-Caicedo, Angel, Sosa, Claudio G., de Mucio, Bremen, Rojas-Suarez, José, Say, Lale, Cresswell, Jenny A., de Francisco, Luis Andrés, Serruya, Suzanne, Lic, Diana Carolina Franco Pulido, Urbina, Luis, Hilaire, Erika Saint, Munayco, César V., Gil, Fabiola, Rousselin, Erick, Contreras, Leonardo, Stefan, Allan, Becerra, Alvinzy Velásquez, Degraff, Evelyn, Espada, Franco, Conde, Victor, Mery, Gustavo, Castaño, Víctor Hugo Álvarez, Umbarila, Aura Liliana Torres, Romero, Ivy Lorena Talavera, Alfonso, Yeimy Catherine Rodríguez, Lovato Silva, Raquel, Calle, Jakeline, Díaz -Viscensini, Cynthia Marlene, Frutos, Vicente Nicolas Bataglia, Laguardia, Elodia Vysokolán, Padilla, Haydee, Ciganda, Alvaro, Colomar, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073212/
https://www.ncbi.nlm.nih.gov/pubmed/35539820
http://dx.doi.org/10.1016/j.lana.2022.100269
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author Maza-Arnedo, Fabian
Paternina-Caicedo, Angel
Sosa, Claudio G.
de Mucio, Bremen
Rojas-Suarez, José
Say, Lale
Cresswell, Jenny A.
de Francisco, Luis Andrés
Serruya, Suzanne
Lic, Diana Carolina Franco Pulido
Urbina, Luis
Hilaire, Erika Saint
Munayco, César V.
Gil, Fabiola
Rousselin, Erick
Contreras, Leonardo
Stefan, Allan
Becerra, Alvinzy Velásquez
Degraff, Evelyn
Espada, Franco
Conde, Victor
Mery, Gustavo
Castaño, Víctor Hugo Álvarez
Umbarila, Aura Liliana Torres
Romero, Ivy Lorena Talavera
Alfonso, Yeimy Catherine Rodríguez
Lovato Silva, Raquel
Calle, Jakeline
Díaz -Viscensini, Cynthia Marlene
Frutos, Vicente Nicolas Bataglia
Laguardia, Elodia Vysokolán
Padilla, Haydee
Ciganda, Alvaro
Colomar, Mercedes
author_facet Maza-Arnedo, Fabian
Paternina-Caicedo, Angel
Sosa, Claudio G.
de Mucio, Bremen
Rojas-Suarez, José
Say, Lale
Cresswell, Jenny A.
de Francisco, Luis Andrés
Serruya, Suzanne
Lic, Diana Carolina Franco Pulido
Urbina, Luis
Hilaire, Erika Saint
Munayco, César V.
Gil, Fabiola
Rousselin, Erick
Contreras, Leonardo
Stefan, Allan
Becerra, Alvinzy Velásquez
Degraff, Evelyn
Espada, Franco
Conde, Victor
Mery, Gustavo
Castaño, Víctor Hugo Álvarez
Umbarila, Aura Liliana Torres
Romero, Ivy Lorena Talavera
Alfonso, Yeimy Catherine Rodríguez
Lovato Silva, Raquel
Calle, Jakeline
Díaz -Viscensini, Cynthia Marlene
Frutos, Vicente Nicolas Bataglia
Laguardia, Elodia Vysokolán
Padilla, Haydee
Ciganda, Alvaro
Colomar, Mercedes
author_sort Maza-Arnedo, Fabian
collection PubMed
description BACKGROUND: This study aimed to describe the clinical characteristics of maternal deaths associated with COVID-19 registered in a collaborative Latin-American multi-country database. METHODS: This was an observational study implemented from March 1st 2020 to November 29th 2021 in eight Latin American countries. Information was based on the Perinatal Information System from the Latin American Center for Perinatology, Women and Reproductive Health. We summarized categorical variables as frequencies and percentages and continuous variables into median with interquartile ranges. FINDINGS: We identified a total of 447 deaths. The median maternal age was 31 years. 86·4% of women were infected antepartum, with most of the cases (60·3%) detected in the third trimester of pregnancy. The most frequent symptoms at first consultation and admission were dyspnea (73·0%), fever (69·0%), and cough (59·0%). Organ dysfunction was reported in 90·4% of women during admission. A total of 64·8% women were admitted to critical care for a median length of eight days. In most cases, the death occurred during the puerperium, with a median of seven days between delivery and death. Preterm delivery was the most common perinatal complication (76·9%) and 59·9% were low birth weight. INTERPRETATION: This study describes the characteristics of maternal deaths in a comprehensive multi-country database in Latin America during the COVID-19 pandemic. Barriers faced by Latin American pregnant women to access intensive care services when required were also revealed. Decision-makers should strengthen severity awareness, and referral strategies to avoid potential delays. FUNDING: Latin American Center for Perinatology, Women and Reproductive Health.
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spelling pubmed-90732122022-05-06 Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths Maza-Arnedo, Fabian Paternina-Caicedo, Angel Sosa, Claudio G. de Mucio, Bremen Rojas-Suarez, José Say, Lale Cresswell, Jenny A. de Francisco, Luis Andrés Serruya, Suzanne Lic, Diana Carolina Franco Pulido Urbina, Luis Hilaire, Erika Saint Munayco, César V. Gil, Fabiola Rousselin, Erick Contreras, Leonardo Stefan, Allan Becerra, Alvinzy Velásquez Degraff, Evelyn Espada, Franco Conde, Victor Mery, Gustavo Castaño, Víctor Hugo Álvarez Umbarila, Aura Liliana Torres Romero, Ivy Lorena Talavera Alfonso, Yeimy Catherine Rodríguez Lovato Silva, Raquel Calle, Jakeline Díaz -Viscensini, Cynthia Marlene Frutos, Vicente Nicolas Bataglia Laguardia, Elodia Vysokolán Padilla, Haydee Ciganda, Alvaro Colomar, Mercedes Lancet Reg Health Am Articles BACKGROUND: This study aimed to describe the clinical characteristics of maternal deaths associated with COVID-19 registered in a collaborative Latin-American multi-country database. METHODS: This was an observational study implemented from March 1st 2020 to November 29th 2021 in eight Latin American countries. Information was based on the Perinatal Information System from the Latin American Center for Perinatology, Women and Reproductive Health. We summarized categorical variables as frequencies and percentages and continuous variables into median with interquartile ranges. FINDINGS: We identified a total of 447 deaths. The median maternal age was 31 years. 86·4% of women were infected antepartum, with most of the cases (60·3%) detected in the third trimester of pregnancy. The most frequent symptoms at first consultation and admission were dyspnea (73·0%), fever (69·0%), and cough (59·0%). Organ dysfunction was reported in 90·4% of women during admission. A total of 64·8% women were admitted to critical care for a median length of eight days. In most cases, the death occurred during the puerperium, with a median of seven days between delivery and death. Preterm delivery was the most common perinatal complication (76·9%) and 59·9% were low birth weight. INTERPRETATION: This study describes the characteristics of maternal deaths in a comprehensive multi-country database in Latin America during the COVID-19 pandemic. Barriers faced by Latin American pregnant women to access intensive care services when required were also revealed. Decision-makers should strengthen severity awareness, and referral strategies to avoid potential delays. FUNDING: Latin American Center for Perinatology, Women and Reproductive Health. Elsevier 2022-05-06 /pmc/articles/PMC9073212/ /pubmed/35539820 http://dx.doi.org/10.1016/j.lana.2022.100269 Text en © 2022 Pan American Health Organization https://creativecommons.org/licenses/by/3.0/igo/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/igo/).
spellingShingle Articles
Maza-Arnedo, Fabian
Paternina-Caicedo, Angel
Sosa, Claudio G.
de Mucio, Bremen
Rojas-Suarez, José
Say, Lale
Cresswell, Jenny A.
de Francisco, Luis Andrés
Serruya, Suzanne
Lic, Diana Carolina Franco Pulido
Urbina, Luis
Hilaire, Erika Saint
Munayco, César V.
Gil, Fabiola
Rousselin, Erick
Contreras, Leonardo
Stefan, Allan
Becerra, Alvinzy Velásquez
Degraff, Evelyn
Espada, Franco
Conde, Victor
Mery, Gustavo
Castaño, Víctor Hugo Álvarez
Umbarila, Aura Liliana Torres
Romero, Ivy Lorena Talavera
Alfonso, Yeimy Catherine Rodríguez
Lovato Silva, Raquel
Calle, Jakeline
Díaz -Viscensini, Cynthia Marlene
Frutos, Vicente Nicolas Bataglia
Laguardia, Elodia Vysokolán
Padilla, Haydee
Ciganda, Alvaro
Colomar, Mercedes
Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths
title Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths
title_full Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths
title_fullStr Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths
title_full_unstemmed Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths
title_short Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths
title_sort maternal mortality linked to covid-19 in latin america: results from a multi-country collaborative database of 447 deaths
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073212/
https://www.ncbi.nlm.nih.gov/pubmed/35539820
http://dx.doi.org/10.1016/j.lana.2022.100269
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