Severe varicella in a child immunosuppressed with methotrexate()

Varicella is a common viral infection in childhood and usually has a benign evolution. However, the evolution can be severe in immunosuppressed children. Vaccination can prevent its occurrence and especially the development of severe and/or complicated cases. Methotrexate is a systemic therapeutic o...

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Detalles Bibliográficos
Autores principales: Galvão, Letícia Oba, Reis, Carmelia Matos Santiago, Alves, Natália Lima, Maciel, Elisa Scandiuzzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073232/
https://www.ncbi.nlm.nih.gov/pubmed/35144830
http://dx.doi.org/10.1016/j.abd.2020.10.017
Descripción
Sumario:Varicella is a common viral infection in childhood and usually has a benign evolution. However, the evolution can be severe in immunosuppressed children. Vaccination can prevent its occurrence and especially the development of severe and/or complicated cases. Methotrexate is a systemic therapeutic option for many inflammatory diseases, and its immunosuppressive action exposes its users to a higher susceptibility to infection. The present report describes a case of severe varicella infection in a child immunosuppressed with methotrexate.

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