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miR-21 antagonist alleviates colitis and angiogenesis via the PTEN/PI3K/AKT pathway in colitis mice induced by TNBS

BACKGROUND: The pathogenesis of Crohn’s disease (CD) is unknown; however, angiogenesis is known to play an important role in the disease. The present research suggests that microRNA-21 (miR-21) may play a positive regulatory role in disordered angiogenesis in CD. METHODS: C57 wild-type mice were div...

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Detalles Bibliográficos
Autores principales: Xie, Xiaoran, Liu, Peng, Wu, Hao, Li, Huan, Tang, Yu, Chen, Xiong, Xu, Canxia, Liu, Xiaoming, Dai, Guoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9073802/
https://www.ncbi.nlm.nih.gov/pubmed/35530951
http://dx.doi.org/10.21037/atm-22-944