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AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model

BACKGROUND: Apoptosis signal-regulating kinase 1-interacting protein 1 (AIP1) participates in inflammatory neovascularization induction. NADPH oxidase 4 (NOX4) produces reactive oxygen species (ROS), leading to an imbalance in nucleotide-binding oligomerization domain-like receptor family pyrin doma...

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Detalles Bibliográficos
Autores principales:	Li, Qingyu, Hua, Xia, Li, Liangpin, Zhou, Xueyan, Tian, Ye, Deng, Yang, Zhang, Min, Yuan, Xiaoyong, Chi, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074213/ https://www.ncbi.nlm.nih.gov/pubmed/35524333 http://dx.doi.org/10.1186/s12964-022-00877-5

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