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Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy

BACKGROUND: Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer that develops resistance to chemotherapy frequently. Autophagy has been reported as a pro-survival response to chemotherapeutic drugs in TNBC, and suppression of autophagy can be a strategy to overcome d...

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Detalles Bibliográficos
Autores principales:	Zhang, Shuang, Dong, Yu, Chen, Xiuping, TAN, Chris Soon Heng, Li, Min, Miao, Kai, Lu, Jia-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074333/ https://www.ncbi.nlm.nih.gov/pubmed/35524271 http://dx.doi.org/10.1186/s13020-022-00605-8

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