t-BuOK-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives

A simple, mild and efficient protocol was developed for the alkylation of fluorene with alcohols in the presence of t-BuOK as catalyst, affording the desired 9-monoalkylfluorenes with near quantitative yields in most cases.

Detalles Bibliográficos
Autores principales: Fan, Jiang-Tao, Fan, Xin-Heng, Gao, Cai-Yan, Wang, Zhenpeng, Yang, Lian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074706/
https://www.ncbi.nlm.nih.gov/pubmed/35528057
http://dx.doi.org/10.1039/c9ra07557g
_version_ 1784701528914788352
author Fan, Jiang-Tao
Fan, Xin-Heng
Gao, Cai-Yan
Wang, Zhenpeng
Yang, Lian-Ming
author_facet Fan, Jiang-Tao
Fan, Xin-Heng
Gao, Cai-Yan
Wang, Zhenpeng
Yang, Lian-Ming
author_sort Fan, Jiang-Tao
collection PubMed
description A simple, mild and efficient protocol was developed for the alkylation of fluorene with alcohols in the presence of t-BuOK as catalyst, affording the desired 9-monoalkylfluorenes with near quantitative yields in most cases.
format Online
Article
Text
id pubmed-9074706
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90747062022-05-06 t-BuOK-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives Fan, Jiang-Tao Fan, Xin-Heng Gao, Cai-Yan Wang, Zhenpeng Yang, Lian-Ming RSC Adv Chemistry A simple, mild and efficient protocol was developed for the alkylation of fluorene with alcohols in the presence of t-BuOK as catalyst, affording the desired 9-monoalkylfluorenes with near quantitative yields in most cases. The Royal Society of Chemistry 2019-11-04 /pmc/articles/PMC9074706/ /pubmed/35528057 http://dx.doi.org/10.1039/c9ra07557g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Fan, Jiang-Tao
Fan, Xin-Heng
Gao, Cai-Yan
Wang, Zhenpeng
Yang, Lian-Ming
t-BuOK-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives
title t-BuOK-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives
title_full t-BuOK-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives
title_fullStr t-BuOK-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives
title_full_unstemmed t-BuOK-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives
title_short t-BuOK-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives
title_sort t-buok-catalysed alkylation of fluorene with alcohols: a highly green route to 9-monoalkylfluorene derivatives
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074706/
https://www.ncbi.nlm.nih.gov/pubmed/35528057
http://dx.doi.org/10.1039/c9ra07557g
work_keys_str_mv AT fanjiangtao tbuokcatalysedalkylationoffluorenewithalcoholsahighlygreenrouteto9monoalkylfluorenederivatives
AT fanxinheng tbuokcatalysedalkylationoffluorenewithalcoholsahighlygreenrouteto9monoalkylfluorenederivatives
AT gaocaiyan tbuokcatalysedalkylationoffluorenewithalcoholsahighlygreenrouteto9monoalkylfluorenederivatives
AT wangzhenpeng tbuokcatalysedalkylationoffluorenewithalcoholsahighlygreenrouteto9monoalkylfluorenederivatives
AT yanglianming tbuokcatalysedalkylationoffluorenewithalcoholsahighlygreenrouteto9monoalkylfluorenederivatives

Ejemplares similares