Effects of age, amyloid, sex, and APOE ε4 on the CSF proteome in normal cognition

INTRODUCTION: It is important to understand which biological processes change with aging, and how such changes are associated with increased Alzheimer's disease (AD) risk. We studied how cerebrospinal fluid (CSF) proteomics changed with age and tested if associations depended on amyloid status,...

Descripción completa

Detalles Bibliográficos
Autores principales: Wesenhagen, Kirsten E.J., Gobom, Johan, Bos, Isabelle, Vos, Stephanie J.B., Martinez‐Lage, Pablo, Popp, Julius, Tsolaki, Magda, Vandenberghe, Rik, Freund‐Levi, Yvonne, Verhey, Frans, Lovestone, Simon, Streffer, Johannes, Dobricic, Valerija, Bertram, Lars, Blennow, Kaj, Pikkarainen, Maria, Hallikainen, Merja, Kuusisto, Johanna, Laakso, Markku, Soininen, Hilkka, Scheltens, Philip, Zetterberg, Henrik, Teunissen, Charlotte E., Visser, Pieter Jelle, Tijms, Betty M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Cerebrospinal Fluid Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074716/
https://www.ncbi.nlm.nih.gov/pubmed/35571963
http://dx.doi.org/10.1002/dad2.12286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074716/
https://www.ncbi.nlm.nih.gov/pubmed/35571963
http://dx.doi.org/10.1002/dad2.12286

Ejemplares similares