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The exogenous delivery of microRNA-449b-5p using spermidine-PLGA nanoparticles efficiently decreases hepatic injury

A notable liver ischemia/reperfusion (I/R) injury is observed during liver transplantation, shock, trauma and other systemic diseases. The main aim of the present study was to evaluate the fact that HMGB1 acts as an early mediator of inflammation in hepatic injury and the potential of the miR-449b-5...

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Detalles Bibliográficos
Autores principales: Hu, Fengli, Yang, Dongdong, Qian, Bo, Fan, Shengjie, Zhu, Qiankun, Ren, Haiyang, Li, Xiaodong, Zhai, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074739/
https://www.ncbi.nlm.nih.gov/pubmed/35530696
http://dx.doi.org/10.1039/c9ra06129k

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