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The exogenous delivery of microRNA-449b-5p using spermidine-PLGA nanoparticles efficiently decreases hepatic injury
A notable liver ischemia/reperfusion (I/R) injury is observed during liver transplantation, shock, trauma and other systemic diseases. The main aim of the present study was to evaluate the fact that HMGB1 acts as an early mediator of inflammation in hepatic injury and the potential of the miR-449b-5...
Autores principales: | Hu, Fengli, Yang, Dongdong, Qian, Bo, Fan, Shengjie, Zhu, Qiankun, Ren, Haiyang, Li, Xiaodong, Zhai, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074739/ https://www.ncbi.nlm.nih.gov/pubmed/35530696 http://dx.doi.org/10.1039/c9ra06129k |
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