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Müller Glial Expression of REDD1 Is Required for Retinal Neurodegeneration and Visual Dysfunction in Diabetic Mice
Clinical studies support a role for the protein regulated in development and DNA damage response 1 (REDD1) in ischemic retinal complications. To better understand how REDD1 contributes to retinal pathology, we examined human single-cell sequencing data sets and found specificity of REDD1 expression...
Autores principales: | Miller, William P., Toro, Allyson L., Sunilkumar, Siddharth, Stevens, Shaunaci A., VanCleave, Ashley M., Williamson, David L., Barber, Alistair J., Dennis, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074768/ https://www.ncbi.nlm.nih.gov/pubmed/35167652 http://dx.doi.org/10.2337/db21-0853 |
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