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Epigenetic Regulation of Host Defense Peptide Synthesis: Synergy Between Histone Deacetylase Inhibitors and DNA/Histone Methyltransferase Inhibitors

Host defense peptides (HDPs) are an integral part of the innate immune system acting as the first line of defense. Modulation of HDP synthesis has emerged as a promising host-directed approach to fight against infections. Inhibition of histone deacetylation or DNA methylation is known to enhance HDP...

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Detalles Bibliográficos
Autores principales:	Whitmore, Melanie A., Li, Hong, Lyu, Wentao, Khanam, Sharmily, Zhang, Guolong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074817/ https://www.ncbi.nlm.nih.gov/pubmed/35529861 http://dx.doi.org/10.3389/fimmu.2022.874706

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