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Development of a Personalized Intestinal Fibrosis Model Using Human Intestinal Organoids Derived From Induced Pluripotent Stem Cells

BACKGROUND: Intestinal fibrosis is a serious complication of Crohn’s disease. Numerous cell types including intestinal epithelial and mesenchymal cells are implicated in this process, yet studies are hampered by the lack of personalized in vitro models. Human intestinal organoids (HIOs) derived from...

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Detalles Bibliográficos
Autores principales:	Estrada, Hannah Q, Patel, Shachi, Rabizadeh, Shervin, Casero, David, Targan, Stephan R, Barrett, Robert J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Leading Off
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074870/ https://www.ncbi.nlm.nih.gov/pubmed/34918082 http://dx.doi.org/10.1093/ibd/izab292

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