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HIF1α is dispensable for oocyte development and female fertility in mice

BACKGROUND: It has been thought that oocyte may develop in a low oxygen environment, as changes in follicle structure and formation of a fluid-filled antrum. The survival of hypoxic tissues is controlled by hypoxia-inducible factors (HIFs) that are activated in a low oxygen state. HIF1α is expressed...

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Detalles Bibliográficos
Autores principales: Chen, Yujia, Du, Siyu, Huang, Zhenyue, Han, Longsen, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074875/
https://www.ncbi.nlm.nih.gov/pubmed/35529504
http://dx.doi.org/10.7717/peerj.13370