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Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway

BACKGROUND: Steroid-induced osteonecrosis of the femoral head (SONFH) is a disorder that causes severe disability in patients and has a high incidence worldwide. Although glucocorticoid (GC)-induced apoptosis of osteoblasts is an important cytological basis of SONFH, the detailed mechanism underlyin...

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Detalles Bibliográficos
Autores principales: Sun, Fei, Zhou, Jian Lin, Wei, Si Xing, Jiang, Ze Wen, Peng, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074886/
https://www.ncbi.nlm.nih.gov/pubmed/35529482
http://dx.doi.org/10.7717/peerj.13319

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