Cargando…
Global SLAM-seq for accurate mRNA decay determination and identification of NMD targets
Gene expression analysis requires accurate measurements of global RNA degradation rates, earlier problematic with methods disruptive to cell physiology. Recently, metabolic RNA labeling emerged as an efficient and minimally invasive technique applied in mammalian cells. Here, we have adapted SH-link...
Autores principales: | Alalam, Hanna, Zepeda-Martínez, Jorge A., Sunnerhagen, Per |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074897/ https://www.ncbi.nlm.nih.gov/pubmed/35296539 http://dx.doi.org/10.1261/rna.079077.121 |
Ejemplares similares
-
SLAM‐Drop‐seq reveals mRNA kinetic rates throughout the cell cycle
por: Liu, Haiyue, et al.
Publicado: (2023) -
Environmental stresses suppress nonsense-mediated mRNA decay (NMD) and affect cells by stabilizing NMD-targeted gene expression
por: Usuki, Fusako, et al.
Publicado: (2019) -
A Genetic Trap in Yeast for Inhibitors of SARS-CoV-2 Main Protease
por: Alalam, Hanna, et al.
Publicado: (2021) -
Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies
por: Durand, Sébastien, et al.
Publicado: (2007) -
The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD)
por: Stockklausner, Clemens, et al.
Publicado: (2006)