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UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors

UV light promoted selective oxidation of primary and secondary alcohols has been demonstrated under ‘metal-free’ and ‘additive-free’ conditions. Under the optimized conditions, a variety of aromatic, heteroaromatic, and alicyclic alcohols have been examined for their transformations to the correspon...

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Detalles Bibliográficos
Autores principales: Walia, Preet Kamal, Sharma, Manik, Kumar, Manoj, Bhalla, Vandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074950/
https://www.ncbi.nlm.nih.gov/pubmed/35540607
http://dx.doi.org/10.1039/c9ra06490g
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author Walia, Preet Kamal
Sharma, Manik
Kumar, Manoj
Bhalla, Vandana
author_facet Walia, Preet Kamal
Sharma, Manik
Kumar, Manoj
Bhalla, Vandana
author_sort Walia, Preet Kamal
collection PubMed
description UV light promoted selective oxidation of primary and secondary alcohols has been demonstrated under ‘metal-free’ and ‘additive-free’ conditions. Under the optimized conditions, a variety of aromatic, heteroaromatic, and alicyclic alcohols have been examined for their transformations to the corresponding carbonyl compounds. The mechanistic studies emphasize the important role of substrate (alcohol) and solvent (DMSO) in the generation of superoxide radical which is a vital intermediate for the transformation. This study also highlights the role of air as the oxidant in the oxidation process. Further, the practical application of the strategy has also been demonstrated for the oxidation of the alcoholic moiety in cholesterol.
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spelling pubmed-90749502022-05-09 UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors Walia, Preet Kamal Sharma, Manik Kumar, Manoj Bhalla, Vandana RSC Adv Chemistry UV light promoted selective oxidation of primary and secondary alcohols has been demonstrated under ‘metal-free’ and ‘additive-free’ conditions. Under the optimized conditions, a variety of aromatic, heteroaromatic, and alicyclic alcohols have been examined for their transformations to the corresponding carbonyl compounds. The mechanistic studies emphasize the important role of substrate (alcohol) and solvent (DMSO) in the generation of superoxide radical which is a vital intermediate for the transformation. This study also highlights the role of air as the oxidant in the oxidation process. Further, the practical application of the strategy has also been demonstrated for the oxidation of the alcoholic moiety in cholesterol. The Royal Society of Chemistry 2019-11-06 /pmc/articles/PMC9074950/ /pubmed/35540607 http://dx.doi.org/10.1039/c9ra06490g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Walia, Preet Kamal
Sharma, Manik
Kumar, Manoj
Bhalla, Vandana
UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors
title UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors
title_full UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors
title_fullStr UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors
title_full_unstemmed UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors
title_short UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors
title_sort uv light promoted ‘metal’/‘additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074950/
https://www.ncbi.nlm.nih.gov/pubmed/35540607
http://dx.doi.org/10.1039/c9ra06490g
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