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UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors
UV light promoted selective oxidation of primary and secondary alcohols has been demonstrated under ‘metal-free’ and ‘additive-free’ conditions. Under the optimized conditions, a variety of aromatic, heteroaromatic, and alicyclic alcohols have been examined for their transformations to the correspon...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074950/ https://www.ncbi.nlm.nih.gov/pubmed/35540607 http://dx.doi.org/10.1039/c9ra06490g |
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author | Walia, Preet Kamal Sharma, Manik Kumar, Manoj Bhalla, Vandana |
author_facet | Walia, Preet Kamal Sharma, Manik Kumar, Manoj Bhalla, Vandana |
author_sort | Walia, Preet Kamal |
collection | PubMed |
description | UV light promoted selective oxidation of primary and secondary alcohols has been demonstrated under ‘metal-free’ and ‘additive-free’ conditions. Under the optimized conditions, a variety of aromatic, heteroaromatic, and alicyclic alcohols have been examined for their transformations to the corresponding carbonyl compounds. The mechanistic studies emphasize the important role of substrate (alcohol) and solvent (DMSO) in the generation of superoxide radical which is a vital intermediate for the transformation. This study also highlights the role of air as the oxidant in the oxidation process. Further, the practical application of the strategy has also been demonstrated for the oxidation of the alcoholic moiety in cholesterol. |
format | Online Article Text |
id | pubmed-9074950 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-90749502022-05-09 UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors Walia, Preet Kamal Sharma, Manik Kumar, Manoj Bhalla, Vandana RSC Adv Chemistry UV light promoted selective oxidation of primary and secondary alcohols has been demonstrated under ‘metal-free’ and ‘additive-free’ conditions. Under the optimized conditions, a variety of aromatic, heteroaromatic, and alicyclic alcohols have been examined for their transformations to the corresponding carbonyl compounds. The mechanistic studies emphasize the important role of substrate (alcohol) and solvent (DMSO) in the generation of superoxide radical which is a vital intermediate for the transformation. This study also highlights the role of air as the oxidant in the oxidation process. Further, the practical application of the strategy has also been demonstrated for the oxidation of the alcoholic moiety in cholesterol. The Royal Society of Chemistry 2019-11-06 /pmc/articles/PMC9074950/ /pubmed/35540607 http://dx.doi.org/10.1039/c9ra06490g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Walia, Preet Kamal Sharma, Manik Kumar, Manoj Bhalla, Vandana UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors |
title | UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors |
title_full | UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors |
title_fullStr | UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors |
title_full_unstemmed | UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors |
title_short | UV light promoted ‘Metal’/‘Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors |
title_sort | uv light promoted ‘metal’/‘additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074950/ https://www.ncbi.nlm.nih.gov/pubmed/35540607 http://dx.doi.org/10.1039/c9ra06490g |
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