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PGC-1α deficiency reveals sex-specific links between cardiac energy metabolism and EC-coupling during development of heart failure in mice
AIMS: Biological sex has fundamental effects on mammalian heart physiology and pathogenesis. While it has been established that female sex is a protective factor against most cardiovascular diseases (CVDs), this beneficial effect may involve pathways associated with cardiac energy metabolism. Our ai...
Autores principales: | Naumenko, Nikolay, Mutikainen, Maija, Holappa, Lari, Ruas, Jorge L, Tuomainen, Tomi, Tavi, Pasi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074965/ https://www.ncbi.nlm.nih.gov/pubmed/34086875 http://dx.doi.org/10.1093/cvr/cvab188 |
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