Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size

AIMS: Identifying novel mediators of lethal myocardial reperfusion injury that can be targeted during primary percutaneous coronary intervention (PPCI) is key to limiting the progression of patients with ST-elevation myocardial infarction (STEMI) to heart failure. Here, we show through parallel clin...

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Detalles Bibliográficos
Autores principales: He, Weihong, McCarroll, Charlotte S, Nather, Katrin, Ford, Kristopher, Mangion, Kenneth, Riddell, Alexandra, O’Toole, Dylan, Zaeri, Ali, Corcoran, David, Carrick, David, Lee, Mathew M Y, McEntegart, Margaret, Davie, Andrew, Good, Richard, Lindsay, Mitchell M, Eteiba, Hany, Rocchiccioli, Paul, Watkins, Stuart, Hood, Stuart, Shaukat, Aadil, McArthur, Lisa, Elliott, Elspeth B, McClure, John, Hawksby, Catherine, Martin, Tamara, Petrie, Mark C, Oldroyd, Keith G, Smith, Godfrey L, Channon, Keith M, Berry, Colin, Nicklin, Stuart A, Loughrey, Christopher M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074968/
https://www.ncbi.nlm.nih.gov/pubmed/34132807
http://dx.doi.org/10.1093/cvr/cvab204

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