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Primary cilia control endothelial permeability by regulating expression and location of junction proteins

AIMS: Wall shear stress (WSS) determines intracranial aneurysm (IA) development. Polycystic kidney disease (PKD) patients have a high IA incidence and risk of rupture. Dysfunction/absence of primary cilia in PKD endothelial cells (ECs) may impair mechano-transduction of WSS and favour vascular disor...

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Detalles Bibliográficos
Autores principales: Diagbouga, Mannekomba R, Morel, Sandrine, Cayron, Anne F, Haemmerli, Julien, Georges, Marc, Hierck, Beerend P, Allémann, Eric, Lemeille, Sylvain, Bijlenga, Philippe, Kwak, Brenda R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9074981/
https://www.ncbi.nlm.nih.gov/pubmed/33974072
http://dx.doi.org/10.1093/cvr/cvab165