Safety and Efficacy of Bis-Glyceryl Ascorbate as Prophylaxis for Hand-Foot Skin Reaction: A Single-Arm, Open-Label Phase I/II Study (DGA Study)

BACKGROUND: Hand-foot skin reaction (HFSR) induced by multiple tyrosine kinase inhibitors (TKIs) is a serious side effect that can cause treatment interruption or decreased dosing. This study was conducted to evaluate the safety and efficacy of bis-glyceryl ascorbate (Amitose bis(di)-glyceryl ascorb...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kazuhiro, Nishiyama, Satoshi, Kunisada, Makoto, Iida, Masashi, Ito, Takahiro, Ioroi, Takeshi, Makimoto, Hiroo, Omura, Tomohiro, Harada, Kenichi, Fujisawa, Masato, Nishigori, Chikako, Yano, Ikuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Clinical Trial Results
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075006/
https://www.ncbi.nlm.nih.gov/pubmed/35285503
http://dx.doi.org/10.1093/oncolo/oyab067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075006/
https://www.ncbi.nlm.nih.gov/pubmed/35285503
http://dx.doi.org/10.1093/oncolo/oyab067

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