Cargando…
Trends in Premature Mortality From Acute Myocardial Infarction in the United States, 1999 to 2019
BACKGROUND: Evaluating premature (<65 years of age) mortality because of acute myocardial infarction (AMI) by demographic and regional characteristics may inform public health interventions. METHODS AND RESULTS: We used the Centers for Disease Control and Prevention’s WONDER (Wide‐Ranging Online...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075205/ https://www.ncbi.nlm.nih.gov/pubmed/34935456 http://dx.doi.org/10.1161/JAHA.121.021682 |
_version_ | 1784701628949987328 |
---|---|
author | Dani, Sourbha S. Lone, Ahmad N. Javed, Zulqarnain Khan, Muhammad S. Zia Khan, Muhammad Kaluski, Edo Virani, Salim S. Shapiro, Michael D. Cainzos‐Achirica, Miguel Nasir, Khurram Khan, Safi U. |
author_facet | Dani, Sourbha S. Lone, Ahmad N. Javed, Zulqarnain Khan, Muhammad S. Zia Khan, Muhammad Kaluski, Edo Virani, Salim S. Shapiro, Michael D. Cainzos‐Achirica, Miguel Nasir, Khurram Khan, Safi U. |
author_sort | Dani, Sourbha S. |
collection | PubMed |
description | BACKGROUND: Evaluating premature (<65 years of age) mortality because of acute myocardial infarction (AMI) by demographic and regional characteristics may inform public health interventions. METHODS AND RESULTS: We used the Centers for Disease Control and Prevention’s WONDER (Wide‐Ranging Online Data for Epidemiologic Research) death certificate database to examine premature (<65 years of age) age‐adjusted AMI mortality rates per 100 000 and average annual percentage change from 1999 to 2019. Overall, the age‐adjusted AMI mortality rate was 13.4 (95% CI, 13.3–13.5). Middle‐aged adults, men, non‐Hispanic Black adults, and rural counties had higher mortality than young adults, women, NH White adults, and urban counties, respectively. Between 1999 and 2019, the age‐adjusted AMI mortality rate decreased at an average annual percentage change of −3.4 per year (95% CI, −3.6 to −3.3), with the average annual percentage change showing higher decline in age‐adjusted AMI mortality rates among large (−4.2 per year [95% CI, −4.4 to −4.0]), and medium/small metros (−3.3 per year [95% CI, −3.5 to −3.1]) than rural counties (−2.4 per year [95% CI, −2.8 to −1.9]). Age‐adjusted AMI mortality rates >90th percentile were distributed in the Southern states, and those with mortality <10th percentile were clustered in the Western and Northeastern states. After an initial decline between 1999 and 2011 (−4.3 per year [95% CI, −4.6 to −4.1]), the average annual percentage change showed deceleration in mortality since 2011 (−2.1 per year [95% CI, −2.4 to −1.8]). These trends were consistent across both sexes, all ethnicities and races, and urban/rural counties. CONCLUSIONS: During the past 20 years, decline in premature AMI mortality has slowed down in the United States since 2011, with considerable heterogeneity across demographic groups, states, and urbanicity. Systemic efforts are mandated to address cardiovascular health disparities and outcomes among nonelderly adults. |
format | Online Article Text |
id | pubmed-9075205 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-90752052022-05-10 Trends in Premature Mortality From Acute Myocardial Infarction in the United States, 1999 to 2019 Dani, Sourbha S. Lone, Ahmad N. Javed, Zulqarnain Khan, Muhammad S. Zia Khan, Muhammad Kaluski, Edo Virani, Salim S. Shapiro, Michael D. Cainzos‐Achirica, Miguel Nasir, Khurram Khan, Safi U. J Am Heart Assoc Original Research BACKGROUND: Evaluating premature (<65 years of age) mortality because of acute myocardial infarction (AMI) by demographic and regional characteristics may inform public health interventions. METHODS AND RESULTS: We used the Centers for Disease Control and Prevention’s WONDER (Wide‐Ranging Online Data for Epidemiologic Research) death certificate database to examine premature (<65 years of age) age‐adjusted AMI mortality rates per 100 000 and average annual percentage change from 1999 to 2019. Overall, the age‐adjusted AMI mortality rate was 13.4 (95% CI, 13.3–13.5). Middle‐aged adults, men, non‐Hispanic Black adults, and rural counties had higher mortality than young adults, women, NH White adults, and urban counties, respectively. Between 1999 and 2019, the age‐adjusted AMI mortality rate decreased at an average annual percentage change of −3.4 per year (95% CI, −3.6 to −3.3), with the average annual percentage change showing higher decline in age‐adjusted AMI mortality rates among large (−4.2 per year [95% CI, −4.4 to −4.0]), and medium/small metros (−3.3 per year [95% CI, −3.5 to −3.1]) than rural counties (−2.4 per year [95% CI, −2.8 to −1.9]). Age‐adjusted AMI mortality rates >90th percentile were distributed in the Southern states, and those with mortality <10th percentile were clustered in the Western and Northeastern states. After an initial decline between 1999 and 2011 (−4.3 per year [95% CI, −4.6 to −4.1]), the average annual percentage change showed deceleration in mortality since 2011 (−2.1 per year [95% CI, −2.4 to −1.8]). These trends were consistent across both sexes, all ethnicities and races, and urban/rural counties. CONCLUSIONS: During the past 20 years, decline in premature AMI mortality has slowed down in the United States since 2011, with considerable heterogeneity across demographic groups, states, and urbanicity. Systemic efforts are mandated to address cardiovascular health disparities and outcomes among nonelderly adults. John Wiley and Sons Inc. 2021-12-22 /pmc/articles/PMC9075205/ /pubmed/34935456 http://dx.doi.org/10.1161/JAHA.121.021682 Text en © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Research Dani, Sourbha S. Lone, Ahmad N. Javed, Zulqarnain Khan, Muhammad S. Zia Khan, Muhammad Kaluski, Edo Virani, Salim S. Shapiro, Michael D. Cainzos‐Achirica, Miguel Nasir, Khurram Khan, Safi U. Trends in Premature Mortality From Acute Myocardial Infarction in the United States, 1999 to 2019 |
title | Trends in Premature Mortality From Acute Myocardial Infarction in the United States, 1999 to 2019 |
title_full | Trends in Premature Mortality From Acute Myocardial Infarction in the United States, 1999 to 2019 |
title_fullStr | Trends in Premature Mortality From Acute Myocardial Infarction in the United States, 1999 to 2019 |
title_full_unstemmed | Trends in Premature Mortality From Acute Myocardial Infarction in the United States, 1999 to 2019 |
title_short | Trends in Premature Mortality From Acute Myocardial Infarction in the United States, 1999 to 2019 |
title_sort | trends in premature mortality from acute myocardial infarction in the united states, 1999 to 2019 |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075205/ https://www.ncbi.nlm.nih.gov/pubmed/34935456 http://dx.doi.org/10.1161/JAHA.121.021682 |
work_keys_str_mv | AT danisourbhas trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT loneahmadn trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT javedzulqarnain trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT khanmuhammads trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT ziakhanmuhammad trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT kaluskiedo trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT viranisalims trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT shapiromichaeld trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT cainzosachiricamiguel trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT nasirkhurram trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 AT khansafiu trendsinprematuremortalityfromacutemyocardialinfarctionintheunitedstates1999to2019 |