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Transient Hypogonadism Is Associated With Heart Rate–Corrected QT Prolongation and Torsades de Pointes Risk During Active Systemic Inflammation in Men

BACKGROUND: Systemic inflammation and male hypogonadism are 2 increasingly recognized “nonconventional” risk factors for long‐QT syndrome and torsades de pointes (TdP). Specifically, inflammatory cytokines prolong, while testosterone shortens the heart rate–corrected QT interval (QTc) via direct ele...

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Detalles Bibliográficos
Autores principales: Lazzerini, Pietro Enea, Cantara, Silvia, Bertolozzi, Iacopo, Accioli, Riccardo, Salvini, Viola, Cartocci, Alessandra, D’Errico, Antonio, Sestini, Fausta, Bisogno, Stefania, Cevenini, Gabriele, Capecchi, Matteo, Laghi‐Pasini, Franco, Castagna, Maria Grazia, Acampa, Maurizio, Boutjdir, Mohamed, Capecchi, Pier Leopoldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075210/
https://www.ncbi.nlm.nih.gov/pubmed/34935398
http://dx.doi.org/10.1161/JAHA.121.023371