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Changes in protein hydration dynamics by encapsulation or crowding of ubiquitin: strong correlation between time-dependent Stokes shift and intermolecular nuclear Overhauser effect

The local changes in protein hydration dynamics upon encapsulation of the protein or macromolecular crowding are essential to understand protein function in cellular environments. We were able to obtain a spatially-resolved picture of the influence of confinement and crowding on the hydration dynami...

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Detalles Bibliográficos
Autores principales: Honegger, Philipp, Heid, Esther, Schmode, Stella, Schröder, Christian, Steinhauser, Othmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075347/
https://www.ncbi.nlm.nih.gov/pubmed/35539058
http://dx.doi.org/10.1039/c9ra08008b