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Histone Methyltransferase Dot1L Contributes to RIPK1 Kinase‐Dependent Apoptosis in Cerebral Ischemia/Reperfusion

BACKGROUND: Neuron apoptosis is a pivotal process for brain damage in cerebral ischemia. Dot1L (disruptor of telomeric silencing 1‐like) is only known histone H3K79 methyltransferase. It is not clear whether the role and mechanism of Dot1L on cerebral ischemia is related to regulate neuron apoptosis...

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Detalles Bibliográficos
Autores principales:	Wang, Jinghuan, Zhong, Wen, Su, Haibi, Xu, Jie, Yang, Di, Liu, Xinhua, Zhu, Yi Zhun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075366/ https://www.ncbi.nlm.nih.gov/pubmed/34796721 http://dx.doi.org/10.1161/JAHA.121.022791

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