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Real‐Time Arrhythmia Detection Using Hybrid Convolutional Neural Networks

BACKGROUND: Accurate detection of arrhythmic events in the intensive care units (ICU) is of paramount significance in providing timely care. However, traditional ICU monitors generate a high rate of false alarms causing alarm fatigue. In this work, we develop an algorithm to improve life threatening...

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Autores principales: Bollepalli, Sandeep Chandra, Sevakula, Rahul K., Au‐Yeung, Wan‐Tai M., Kassab, Mohamad B., Merchant, Faisal M., Bazoukis, George, Boyer, Richard, Isselbacher, Eric M., Armoundas, Antonis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075394/
https://www.ncbi.nlm.nih.gov/pubmed/34854319
http://dx.doi.org/10.1161/JAHA.121.023222
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author Bollepalli, Sandeep Chandra
Sevakula, Rahul K.
Au‐Yeung, Wan‐Tai M.
Kassab, Mohamad B.
Merchant, Faisal M.
Bazoukis, George
Boyer, Richard
Isselbacher, Eric M.
Armoundas, Antonis A.
author_facet Bollepalli, Sandeep Chandra
Sevakula, Rahul K.
Au‐Yeung, Wan‐Tai M.
Kassab, Mohamad B.
Merchant, Faisal M.
Bazoukis, George
Boyer, Richard
Isselbacher, Eric M.
Armoundas, Antonis A.
author_sort Bollepalli, Sandeep Chandra
collection PubMed
description BACKGROUND: Accurate detection of arrhythmic events in the intensive care units (ICU) is of paramount significance in providing timely care. However, traditional ICU monitors generate a high rate of false alarms causing alarm fatigue. In this work, we develop an algorithm to improve life threatening arrhythmia detection in the ICUs using a deep learning approach. METHODS AND RESULTS: This study involves a total of 953 independent life‐threatening arrhythmia alarms generated from the ICU bedside monitors of 410 patients. Specifically, we used the ECG (4 channels), arterial blood pressure, and photoplethysmograph signals to accurately detect the onset and offset of various arrhythmias, without prior knowledge of the alarm type. We used a hybrid convolutional neural network based classifier that fuses traditional handcrafted features with features automatically learned using convolutional neural networks. Further, the proposed architecture remains flexible to be adapted to various arrhythmic conditions as well as multiple physiological signals. Our hybrid‐ convolutional neural network approach achieved superior performance compared with methods which only used convolutional neural network. We evaluated our algorithm using 5‐fold cross‐validation for 5 times and obtained an accuracy of 87.5%±0.5%, and a score of 81%±0.9%. Independent evaluation of our algorithm on the publicly available PhysioNet 2015 Challenge database resulted in overall classification accuracy and score of 93.9% and 84.3%, respectively, indicating its efficacy and generalizability. CONCLUSIONS: Our method accurately detects multiple arrhythmic conditions. Suitable translation of our algorithm may significantly improve the quality of care in ICUs by reducing the burden of false alarms.
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spelling pubmed-90753942022-05-10 Real‐Time Arrhythmia Detection Using Hybrid Convolutional Neural Networks Bollepalli, Sandeep Chandra Sevakula, Rahul K. Au‐Yeung, Wan‐Tai M. Kassab, Mohamad B. Merchant, Faisal M. Bazoukis, George Boyer, Richard Isselbacher, Eric M. Armoundas, Antonis A. J Am Heart Assoc Original Research BACKGROUND: Accurate detection of arrhythmic events in the intensive care units (ICU) is of paramount significance in providing timely care. However, traditional ICU monitors generate a high rate of false alarms causing alarm fatigue. In this work, we develop an algorithm to improve life threatening arrhythmia detection in the ICUs using a deep learning approach. METHODS AND RESULTS: This study involves a total of 953 independent life‐threatening arrhythmia alarms generated from the ICU bedside monitors of 410 patients. Specifically, we used the ECG (4 channels), arterial blood pressure, and photoplethysmograph signals to accurately detect the onset and offset of various arrhythmias, without prior knowledge of the alarm type. We used a hybrid convolutional neural network based classifier that fuses traditional handcrafted features with features automatically learned using convolutional neural networks. Further, the proposed architecture remains flexible to be adapted to various arrhythmic conditions as well as multiple physiological signals. Our hybrid‐ convolutional neural network approach achieved superior performance compared with methods which only used convolutional neural network. We evaluated our algorithm using 5‐fold cross‐validation for 5 times and obtained an accuracy of 87.5%±0.5%, and a score of 81%±0.9%. Independent evaluation of our algorithm on the publicly available PhysioNet 2015 Challenge database resulted in overall classification accuracy and score of 93.9% and 84.3%, respectively, indicating its efficacy and generalizability. CONCLUSIONS: Our method accurately detects multiple arrhythmic conditions. Suitable translation of our algorithm may significantly improve the quality of care in ICUs by reducing the burden of false alarms. John Wiley and Sons Inc. 2021-12-02 /pmc/articles/PMC9075394/ /pubmed/34854319 http://dx.doi.org/10.1161/JAHA.121.023222 Text en © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Bollepalli, Sandeep Chandra
Sevakula, Rahul K.
Au‐Yeung, Wan‐Tai M.
Kassab, Mohamad B.
Merchant, Faisal M.
Bazoukis, George
Boyer, Richard
Isselbacher, Eric M.
Armoundas, Antonis A.
Real‐Time Arrhythmia Detection Using Hybrid Convolutional Neural Networks
title Real‐Time Arrhythmia Detection Using Hybrid Convolutional Neural Networks
title_full Real‐Time Arrhythmia Detection Using Hybrid Convolutional Neural Networks
title_fullStr Real‐Time Arrhythmia Detection Using Hybrid Convolutional Neural Networks
title_full_unstemmed Real‐Time Arrhythmia Detection Using Hybrid Convolutional Neural Networks
title_short Real‐Time Arrhythmia Detection Using Hybrid Convolutional Neural Networks
title_sort real‐time arrhythmia detection using hybrid convolutional neural networks
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075394/
https://www.ncbi.nlm.nih.gov/pubmed/34854319
http://dx.doi.org/10.1161/JAHA.121.023222
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