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Spontaneous Degenerative Aortic Valve Disease in New Zealand Obese Mice

BACKGROUND: Degenerative aortic valve (AoV) disease and resulting aortic stenosis are major clinical health problems. Murine models of valve disease are rare, resulting in a translational knowledge gap on underlying mechanisms, functional consequences, and potential therapies. Naïve New Zealand obes...

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Detalles Bibliográficos
Autores principales:	Ott, Christiane, Pappritz, Kathleen, Hegemann, Niklas, John, Cathleen, Jeuthe, Sarah, McAlpine, Cameron S., Iwamoto, Yoshiko, Lauryn, Jonathan H., Klages, Jan, Klopfleisch, Robert, Van Linthout, Sophie, Swirski, Fil, Nahrendorf, Matthias, Kintscher, Ulrich, Grune, Tilman, Kuebler, Wolfgang M., Grune, Jana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075397/ https://www.ncbi.nlm.nih.gov/pubmed/34779224 http://dx.doi.org/10.1161/JAHA.121.023131

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