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Migraine‐Associated Mutation in the Na,K‐ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function

BACKGROUND: Mutations in ATP1A2 gene encoding the Na,K‐ATPase α(2) isoform are associated with familial hemiplegic migraine type 2. Migraine with aura is a known risk factor for heart disease. The Na,K‐ATPase is important for cardiac function, but its role for heart disease remains unknown. We hypot...

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Detalles Bibliográficos
Autores principales: Staehr, Christian, Rohde, Palle Duun, Krarup, Nikolaj Thure, Ringgaard, Steffen, Laustsen, Christoffer, Johnsen, Jacob, Nielsen, Rikke, Beck, Hans Christian, Morth, Jens Preben, Lykke‐Hartmann, Karin, Jespersen, Nichlas Riise, Abramochkin, Denis, Nyegaard, Mette, Bøtker, Hans Erik, Aalkjaer, Christian, Matchkov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075430/
https://www.ncbi.nlm.nih.gov/pubmed/35289188
http://dx.doi.org/10.1161/JAHA.121.021814