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Therapeutic polymeric nanomedicine: GSH-responsive release promotes drug release for cancer synergistic chemotherapy

To obtain an efficient dual-drug release and enhance therapeutic efficiency for combination chemotherapy, a glutathione (GSH)-responsive therapeutic amphiphilic polyprodrug copolymer (mPEG-b-PCPT) is synthesized to load doxorubicin (DOX) via hydrophobic and π–π stacking interaction. In this nanomedi...

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Detalles Bibliográficos
Autores principales:	Shen, Jie, Wang, Qiwen, Fang, Jie, Shen, Wangxing, Wu, Dan, Tang, Guping, Yang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075505/ https://www.ncbi.nlm.nih.gov/pubmed/35542287 http://dx.doi.org/10.1039/c9ra07051f

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