Cargando…

The effects of trace metal impurities on Ga-68-radiolabelling with a tris(3-hydroxy-1,6-dimethylpyridin-4-one) (THP) chelator

GMP-grade (68)Ge/(68)Ga generators provide access to positron-emitting (68)Ga, enabling preparation of Positron Emission Tomography (PET) tracers and PET imaging at sites that do not have access to cyclotron-produced radionuclides. Radiotracers based on tris(3-hydroxy-1,6-dimethylpyridin-4-one) (THP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cusnir, Ruslan, Cakebread, Andrew, Cooper, Margaret S., Young, Jennifer D., Blower, Philip J., Ma, Michelle T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075519/ https://www.ncbi.nlm.nih.gov/pubmed/35542301 http://dx.doi.org/10.1039/c9ra07723e

Ejemplares similares

Comparison of macrocyclic and acyclic chelators for gallium-68 radiolabelling
por: Tsionou, Maria Iris, et al.
Publicado: (2017)

Manipulating the In Vivo Behaviour of (68)Ga with Tris(Hydroxypyridinone) Chelators: Pretargeting and Blood Clearance
por: Imberti, Cinzia, et al.
Publicado: (2020)

Tuning the properties of tris(hydroxypyridinone) ligands: efficient (68)Ga chelators for PET imaging
por: Imberti, Cinzia, et al.
Publicado: (2019)

Hydroxypyridinone Chelators: From Iron Scavenging to Radiopharmaceuticals for PET Imaging with Gallium-68
por: Cusnir, Ruslan, et al.
Publicado: (2017)

Simple, mild, one-step labelling of proteins with gallium-68 using a tris(hydroxypyridinone) bifunctional chelator: a (68)Ga-THP-scFv targeting the prostate-specific membrane antigen
por: Nawaz, Saima, et al.
Publicado: (2017)

New Tris(hydroxypyridinone) Bifunctional Chelators Containing Isothiocyanate Groups Provide a Versatile Platform for Rapid One-Step Labeling and PET Imaging with (68)Ga(3+)
por: Ma, Michelle T., et al.
Publicado: (2015)

Fusarinine C, a novel siderophore‐based bifunctional chelator for radiolabeling with Gallium‐68
por: Zhai, Chuangyan, et al.
Publicado: (2015)

Evaluation of (68)Ga-Radiolabeled Peptides for HER2 PET Imaging
por: Ducharme, Maxwell, et al.
Publicado: (2022)

The management impact of (68)gallium-tris(hydroxypyridinone) prostate-specific membrane antigen ((68)Ga-THP-PSMA) PET-CT imaging for high-risk and biochemically recurrent prostate cancer
por: Kulkarni, Meghana, et al.
Publicado: (2019)

Biodistribution of (68/67)Ga-Radiolabeled Sphingolipid Nanoemulsions by PET and SPECT Imaging
por: Díez-Villares, Sandra, et al.
Publicado: (2021)

Instant kit preparation of (68)Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [(68)Ga]Ga-DATA-TOC
por: Sinnes, Jean-Philippe, et al.
Publicado: (2019)

Rapid kit-based (68)Ga-labelling and PET imaging with THP-Tyr(3)-octreotate: a preliminary comparison with DOTA-Tyr(3)-octreotate
por: Ma, Michelle T., et al.
Publicado: (2015)

Comparative evaluation of (68)Ga-labelled TATEs: the impact of chelators on imaging
por: Xia, Yuxiao, et al.
Publicado: (2020)

Preparation, Characterization, and Radiolabeling of [(68)Ga]Ga-NODAGA-Pamidronic Acid: A Potential PET Bone Imaging Agent
por: Ashhar, Zarif, et al.
Publicado: (2020)

Fully automated radiolabeling of [(68)Ga]Ga-EMP100 targeting c-MET for PET-CT clinical imaging
por: Rusu, Timofei, et al.
Publicado: (2023)

Site-Specific (68)Ga Radiolabeling of Trastuzumab Fab via Methionine for ImmunoPET Imaging
por: Yue, Thomas T. C., et al.
Publicado: (2023)

A Brief Review of Chelators for Radiolabeling Oligomers
por: Liu, Yuxia, et al.
Publicado: (2010)

Standardization of the [(68)Ga]Ga-PSMA-11 Radiolabeling Protocol in an Automatic Synthesis Module: Assessments for PET Imaging of Prostate Cancer
por: Fuscaldi, Leonardo L., et al.
Publicado: (2021)

Synthesis, Radiolabeling, and Preliminary in vivo Evaluation of [(68)Ga] IPCAT-NOTA as an Imaging Agent for Dopamine Transporter
por: Farn, Shiou-Shiow, et al.
Publicado: (2021)

Preliminary Evaluation of Iron Oxide Nanoparticles Radiolabeled with (68)Ga and (177)Lu as Potential Theranostic Agents
por: Salvanou, Evangelia-Alexandra, et al.
Publicado: (2022)

Heptadentate chelates for (89)Zr-radiolabelling of monoclonal antibodies
por: Guillou, Amaury, et al.
Publicado: (2022)

(68)Ga-Radiolabeling and Pharmacological Characterization of a Kit-Based Formulation of the Gastrin-Releasing Peptide Receptor (GRP-R) Antagonist RM2 for Convenient Preparation of [(68)Ga]Ga-RM2
por: Chastel, Adrien, et al.
Publicado: (2021)

Comparison of 99mTc radiolabeled somatostatin antagonist with [(68) Ga]Ga-DOTA-TATE in a patient with advanced neuroendocrine tumor
por: Opalinska, Marta, et al.
Publicado: (2023)

Ethanol effects on (68)Ga-radiolabelling efficacy and radiolysis in automated synthesis utilizing NaCl post-processing
por: Meisenheimer, Michael, et al.
Publicado: (2019)

Preparation and Preliminary Evaluation of Neurotensin Radiolabelled with (68)Ga and (177)Lu as Potential Theranostic Agent for Colon Cancer
por: Leonte, Radu Anton, et al.
Publicado: (2021)

Preclinical evaluation of (68)Ga-radiolabeled trimeric affibody for PDGFRβ-targeting PET imaging of hepatocellular carcinoma
por: Cai, Huawei, et al.
Publicado: (2023)

Chelator-Free/Chelator-Mediated Radiolabeling of Colloidally Stabilized Iron Oxide Nanoparticles for Biomedical Imaging
por: Papadopoulou, Sofia, et al.
Publicado: (2021)

Comparison of Radiochemical and Chemical Impurities in Liquid Wastes of Two Different (68)Ge/(68)Ga Generators used in Nuclear Medicine PET Chemistry
por: Uğur, Ayşe, et al.
Publicado: (2021)

NHS-Functionalized THP Derivative for Efficient Synthesis of Kit-Based Precursors for (68)Ga Labeled PET Probes
por: Floresta, Giuseppe, et al.
Publicado: (2021)

TrisOxine abiotic siderophores for technetium complexation: radiolabeling and biodistribution studies
por: Leenhardt, Julien, et al.
Publicado: (2023)

Synthesis and Radiolabelling of DOTA-Linked Glutamine Analogues with (67,68)Ga as Markers for Increased Glutamine Metabolism in Tumour Cells
por: Pellegrini, Paul A., et al.
Publicado: (2013)

Synthesis, radiolabeling, and evaluation of 68Ga-labeled aminoquinoxaline derivative as a potent PFKFB3-targeted PET tracer
por: Chen, Feng, et al.
Publicado: (2023)

Synthesis of a Bifunctional Cross‐Bridged Chelating Agent, Peptide Conjugation, and Comparison of (68)Ga Labeling and Complex Stability Characteristics with Established Chelators
por: Damerow, Helen, et al.
Publicado: (2022)

Targeting integrin αvβ6 with gallium-68 tris (hydroxypyridinone) based PET probes
por: Floresta, Giuseppe, et al.
Publicado: (2022)

Biological Evaluation and Molecular Docking Studies of Dimethylpyridine Derivatives
por: Świątek, Piotr, et al.
Publicado: (2019)

Synthesis of (15)N‐labelled 3,5‐dimethylpyridine
por: Schubert, Mario, et al.
Publicado: (2019)

Maleimido-Functionalized NOTA Derivatives as Bifunctional Chelators for Site-Specific Radiolabeling
por: Förster, Christian, et al.
Publicado: (2011)

Bn(2)DT3A, a Chelator for (68)Ga Positron Emission Tomography: Hydroxide Coordination Increases Biological Stability of [(68)Ga][Ga(Bn(2)DT3A)(OH)](−)
por: Price, Thomas W., et al.
Publicado: (2022)

GMP-compliant (68)Ga radiolabelling in a conventional small-scale radiopharmacy: a feasible approach for routine clinical use
por: Vis, Roeland, et al.
Publicado: (2015)

(68)Ga and (188)Re Starch-Based Microparticles as Theranostic Tool for the Hepatocellular Carcinoma: Radiolabeling and Preliminary In Vivo Rat Studies
por: Verger, Elise, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_muo0gtgn5458t0c60kv7vstecm