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Differential mitochondrial protein interaction profile between human translocator protein and its A147T polymorphism variant

The translocator protein (TSPO) has been implicated in mitochondrial transmembrane cholesterol transport, brain inflammation, and other mitochondrial functions. It is upregulated in glial cells during neuroinflammation in Alzheimer’s disease. High affinity TSPO imaging radioligands are utilized to v...

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Detalles Bibliográficos
Autores principales:	Asih, Prita R., Poljak, Anne, Kassiou, Michael, Ke, Yazi D., Ittner, Lars M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075623/ https://www.ncbi.nlm.nih.gov/pubmed/35522669 http://dx.doi.org/10.1371/journal.pone.0254296

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