Occurrence and Nature of Off-Target Modifications by CRISPR-Cas Genome Editing in Plants

[Image: see text] CRISPR-Cas-based genome editing allows for precise and targeted genetic modification of plants. Nevertheless, unintended off-target edits can arise that might confer risks when present in gene-edited food crops. Through an extensive literature review we gathered information on CRIS...

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Detalles Bibliográficos
Autores principales: Sturme, Mark H. J., van der Berg, Jan Pieter, Bouwman, Lianne M. S., De Schrijver, Adinda, de Maagd, Ruud A., Kleter, Gijs A., Battaglia-de Wilde, Evy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075866/
https://www.ncbi.nlm.nih.gov/pubmed/35548699
http://dx.doi.org/10.1021/acsagscitech.1c00270

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