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Metal-free synthesis of 1,N(6)-ethenoadenines from N(6)-propargyl-adenines via NIS mediated radical cascade reaction

In the present paper, an efficient approach for the construction of 1,N(6)-ethenoadenines from conveniently prepared N(6)-propargyl-adenines is developed. This reaction merges N-iodosuccinimide radical initiation and aerobic aminooxygenation in dioxane. This mild, 5-exo-dig, and metal-free cascade r...

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Detalles Bibliográficos
Autores principales:	Yang, Ruchun, Deng, Si, Dong, Xiang-you, Song, Xianrong, Cai, Hu, Bai, Jiang, Xiao, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075968/ https://www.ncbi.nlm.nih.gov/pubmed/35540232 http://dx.doi.org/10.1039/c9ra09198j

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