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Non-glycosylated SARS-CoV-2 RBD elicited a robust neutralizing antibody response in mice

The glycosylated receptor-binding domain (glycoRBD) of SARS-CoV-2 can induce protective neutralizing antibodies to function as a vaccine. However, it is unclear whether vaccines using non-glycosylated RBD (non-glycoRBD) can induce protective immunity. Here, we report the efficacy of a SARS-CoV-2 non...

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Detalles Bibliográficos
Autores principales: Ke, Qian, Sun, Peng, Wang, Tiantian, Mi, Taotao, Xu, Huifang, Wu, Jun, Liu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075978/
https://www.ncbi.nlm.nih.gov/pubmed/35533747
http://dx.doi.org/10.1016/j.jim.2022.113279