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Development of a cost-effective ovine antibody-based therapy against SARS-CoV-2 infection and contribution of antibodies specific to the spike subunit proteins

Antibodies against SARS-CoV-2 are important to generate protective immunity, with convalescent plasma one of the first therapies approved. An alternative source of polyclonal antibodies suitable for upscaling would be more amendable to regulatory approval and widespread use. In this study, sheep wer...

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Detalles Bibliográficos
Autores principales: Findlay-Wilson, Stephen, Easterbrook, Linda, Smith, Sandra, Pope, Neville, Humphries, Gareth, Schuhmann, Holger, Ngabo, Didier, Rayner, Emma, Otter, Ashley David, Coleman, Tom, Hicks, Bethany, Graham, Victoria Anne, Halkerston, Rachel, Apostolakis, Kostis, Taylor, Stephen, Fotheringham, Susan, Horton, Amanda, Tree, Julia Anne, Wand, Matthew, Hewson, Roger, Dowall, Stuart David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075985/
https://www.ncbi.nlm.nih.gov/pubmed/35533779
http://dx.doi.org/10.1016/j.antiviral.2022.105332