Targeting DCLK1 overcomes 5‐fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β‐catenin pathway‐mediated cancer stemness

BACKGROUND: To date, 5‐fluorouracil‐based chemotherapy is very important for locally advanced or metastatic colorectal cancer (CRC). However, chemotherapy resistance results in tumor recurrence and metastasis, which is a major obstacle for treatment of CRC. METHODS: In the current research, we estab...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lanqing, Zhao, Lei, Lin, Zhenyu, Yu, Dandan, Jin, Min, Zhou, Pengfei, Ren, Jinghua, Cheng, Jing, Yang, Kunyu, Wu, Gang, Zhang, Tao, Zhang, Dejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076011/
https://www.ncbi.nlm.nih.gov/pubmed/35522902
http://dx.doi.org/10.1002/ctm2.743

Ejemplares similares

Ejemplares similares