Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double‐blind, placebo‐controlled Phase 2 trial

BACKGROUND: In patients with atopic dermatitis (AD), Staphylococcus aureus frequently colonizes lesions and is hypothesized to be linked to disease severity and progression. Treatments that reduce S. aureus colonization without significantly affecting the skin commensal microbiota are needed. METHOD...

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Detalles Bibliográficos
Autores principales: Weiss, Anne, Delavenne, Emilie, Matias, Carina, Lagler, Heimo, Simon, Daniel, Li, Ping, Hansen, Jon U., dos Santos, Teresa Pires, Jana, Bimal, Priemel, Petra, Bangert, Christine, Bauer, Martin, Eberl, Sabine, Nussbaumer‐Pröll, Alina, Anne Österreicher, Zoe, Matzneller, Peter, Quint, Tamara, Weber, Maria, Nielsen, Hanne Mørck, Rades, Thomas, Johansen, Helle Krogh, Westh, Henrik, Kim, Wooseong, Mylonakis, Eleftherios, Friis, Christian, Guardabassi, Luca, Pace, John, Lundberg, Carina Vingsbo, M'Zali, Fatima, Butty, Pascal, Sørensen, Nikolaj, Nielsen, Henrik Bjørn, Toft‐Kehler, Rasmus, Guttman‐Yassky, Emma, Stingl, Georg, Zeitlinger, Markus, Sommer, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076020/
https://www.ncbi.nlm.nih.gov/pubmed/35522900
http://dx.doi.org/10.1002/ctm2.790

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