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Highly efficient microwave synthesis of rhodanine and 2-thiohydantoin derivatives and determination of relationships between their chemical structures and antibacterial activity

Here we report studies on the synthesis of 12 new heterocyclic derivatives that differ in three structural motifs and the simultaneous evaluation of the impact of these three variables on the biological properties. The examined compounds are based on rhodanine and 2-thiohydantoin cores equipped with...

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Detalles Bibliográficos
Autores principales: Tejchman, Waldemar, Orwat, Bartosz, Korona-Głowniak, Izabela, Barbasz, Anna, Kownacki, Ireneusz, Latacz, Gniewomir, Handzlik, Jadwiga, Żesławska, Ewa, Malm, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076067/
https://www.ncbi.nlm.nih.gov/pubmed/35540630
http://dx.doi.org/10.1039/c9ra08690k