Sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions

We report an efficient and facile one-pot synthesis of 4-oxo-tetrahydroindoles using sulfamic acid under ball milling conditions. The present protocol for preparation of biologically important 4-oxo-tetrahydroindoles offers several advantages such as mild reaction conditions, improved selectivity an...

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Detalles Bibliográficos
Autores principales: Lambat, Trimurti L., Abdala, Ahmed A., Mahmood, Sami, Ledade, Pankaj V., Chaudhary, Ratiram G., Banerjee, Subhash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076070/
https://www.ncbi.nlm.nih.gov/pubmed/35541403
http://dx.doi.org/10.1039/c9ra08478a
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author Lambat, Trimurti L.
Abdala, Ahmed A.
Mahmood, Sami
Ledade, Pankaj V.
Chaudhary, Ratiram G.
Banerjee, Subhash
author_facet Lambat, Trimurti L.
Abdala, Ahmed A.
Mahmood, Sami
Ledade, Pankaj V.
Chaudhary, Ratiram G.
Banerjee, Subhash
author_sort Lambat, Trimurti L.
collection PubMed
description We report an efficient and facile one-pot synthesis of 4-oxo-tetrahydroindoles using sulfamic acid under ball milling conditions. The present protocol for preparation of biologically important 4-oxo-tetrahydroindoles offers several advantages such as mild reaction conditions, improved selectivity and higher isolated yields. Moreover, solvent-free reaction conditions and the use of ball milling make the present protocol environmentally friendly in nature.
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spelling pubmed-90760702022-05-09 Sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions Lambat, Trimurti L. Abdala, Ahmed A. Mahmood, Sami Ledade, Pankaj V. Chaudhary, Ratiram G. Banerjee, Subhash RSC Adv Chemistry We report an efficient and facile one-pot synthesis of 4-oxo-tetrahydroindoles using sulfamic acid under ball milling conditions. The present protocol for preparation of biologically important 4-oxo-tetrahydroindoles offers several advantages such as mild reaction conditions, improved selectivity and higher isolated yields. Moreover, solvent-free reaction conditions and the use of ball milling make the present protocol environmentally friendly in nature. The Royal Society of Chemistry 2019-12-03 /pmc/articles/PMC9076070/ /pubmed/35541403 http://dx.doi.org/10.1039/c9ra08478a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Lambat, Trimurti L.
Abdala, Ahmed A.
Mahmood, Sami
Ledade, Pankaj V.
Chaudhary, Ratiram G.
Banerjee, Subhash
Sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions
title Sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions
title_full Sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions
title_fullStr Sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions
title_full_unstemmed Sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions
title_short Sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions
title_sort sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076070/
https://www.ncbi.nlm.nih.gov/pubmed/35541403
http://dx.doi.org/10.1039/c9ra08478a
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