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Analysis of antisense oligonucleotides with the use of ionic liquids as mobile phase modifiers

The main goal of this study was the investigation of the impact of several ionic liquids, commonly used as free silanol suppressors, on the retention and separation of phosphorothioate oligonucleotides. Three various stationary phases (octadecyl, octadecyl with embedded polar groups and pentafluorop...

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Detalles Bibliográficos
Autores principales: Kaczmarkiewicz, Anna, Zielak, Judyta, Nuckowski, Łukasz, Studzińska, Sylwia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076077/
https://www.ncbi.nlm.nih.gov/pubmed/35540640
http://dx.doi.org/10.1039/c9ra06483d