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Selective recognition of human telomeric G-quadruplex with designed peptide via hydrogen bonding followed by base stacking interactions
We described a novel synthetic peptide in which a glutamine residue binds through hydrogen bonding to a guanine-base and a trytophan residue intercalates with K(+) resulting in stabilization of a human telomeric G-quadruplex with high selectivity over its complementary c-rich strand and a double-str...
Autores principales: | Tyagi, Shikhar, Saxena, Sarika, Kundu, Nikita, Sharma, Taniya, Chakraborty, Amlan, Kaur, Sarvpreet, Miyoshi, Daisuke, Shankaraswamy, Jadala |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076235/ https://www.ncbi.nlm.nih.gov/pubmed/35542665 http://dx.doi.org/10.1039/c9ra08761c |
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