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CD44-targeted hyaluronic acid–curcumin reverses chemotherapeutics resistance by inhibiting P-gp and anti-apoptotic pathways

Chemotherapeutic drug resistance poses a great challenge in cancer therapy. Drug efflux and anti-apoptotic processes are the two most common mechanisms leading to chemotherapy resistance. In this study, we focused on the applicability of curcumin (CUR) as a sensitizer for chemotherapeutics (doxorubi...

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Detalles Bibliográficos
Autores principales: Diao, Lu, Shen, Ao, Yang, Yunxu, Tao, Jin, Hu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076387/
https://www.ncbi.nlm.nih.gov/pubmed/35540044
http://dx.doi.org/10.1039/c9ra08202f