IL-36 signalling enhances a pro-tumorigenic phenotype in colon cancer cells with cancer cell growth restricted by administration of the IL-36R antagonist

The IL-36 cytokines are a recently described subset of the IL-1 family of cytokines, shown to play a role in the pathogenesis of intestinal diseases such as Inflammatory Bowel Disease (IBD). Given the link between IBD and colitis –associated cancer, as well as the involvement of other IL-1 family me...

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Detalles Bibliográficos
Autores principales: Baker, Kevin, O’Donnell, Charlotte, Bendix, Maura, Keogh, Samuel, Byrne, James, O’Riordain, Michael, Neary, Peter, Houston, Aileen, Brint, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076531/
https://www.ncbi.nlm.nih.gov/pubmed/35365751
http://dx.doi.org/10.1038/s41388-022-02281-2

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