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Maladaptive myelination promotes generalized epilepsy progression

Activity-dependent myelination can fine-tune neural network dynamics. Conversely, aberrant neuronal activity, as occurs in disorders of recurrent seizures (epilepsy), could promote maladaptive myelination, contributing to pathogenesis. In this study, we tested the hypothesis that activity-dependent...

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Detalles Bibliográficos
Autores principales:	Knowles, Juliet K., Xu, Haojun, Soane, Caroline, Batra, Ankita, Saucedo, Tristan, Frost, Eleanor, Tam, Lydia T., Fraga, Danielle, Ni, Lijun, Villar, Katlin, Talmi, Sydney, Huguenard, John R., Monje, Michelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076538/ https://www.ncbi.nlm.nih.gov/pubmed/35501379 http://dx.doi.org/10.1038/s41593-022-01052-2

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