A simple sensitive UFLC-MS/MS method for the simultaneous quantification of artesunate, dihydroartemisinin and quercetin in rat plasma and its application to pharmacokinetic studies

An ultrafast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS) method was developed for the simultaneous estimation of artesunate (ART), dihydroartemisinin (DHA, an active metabolite of ART) and quercetin (QRT) in rat plasma. The separation was achieved using a Zorbax C(18) column (3 μm, 5...

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Detalles Bibliográficos
Autores principales: Puttappa, Nethravathi, Yamjala, Karthik, S. T., Narenderan, Raman, Suresh Kumar, Kuppusamy, Gowthamarajan, Babu, Basuvan, Kumar, P. Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076539/
https://www.ncbi.nlm.nih.gov/pubmed/35541625
http://dx.doi.org/10.1039/c9ra07707c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076539/
https://www.ncbi.nlm.nih.gov/pubmed/35541625
http://dx.doi.org/10.1039/c9ra07707c

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