Triarylethylene-indolin-2,3-dione molecular conjugates: design, synthesis, docking studies and anti-proliferation evaluation

A series of 1H-1,2,3-triazole-linked ospemifene-isatin and O-methylated ospemifene–isatin conjugates were synthesized and assayed for their anti-proliferative activities against estrogen-responsive as well as estrogen-non-responsive cells. The non-cytotoxic conjugate 14e, with an optimal combination...

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Detalles Bibliográficos
Autores principales: Kumar, Sumit, Palma, Gabriella, Perumal, Shanen, Kaur, Mandeep, Singh-Pillay, Ashona, Raj, Raghu, Singh, Parvesh, Kumar, Vipan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076587/
https://www.ncbi.nlm.nih.gov/pubmed/35542879
http://dx.doi.org/10.1039/c9ra08776a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076587/
https://www.ncbi.nlm.nih.gov/pubmed/35542879
http://dx.doi.org/10.1039/c9ra08776a

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