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Stage IV colon cancer patients without DENND2D expression benefit more from neoadjuvant chemotherapy
According to the EPOC study, chemotherapy could improve 5-year disease-free survival of stage IV colon cancer patients by 8.1%. However, more molecular biomarkers are required to identify patients who need neoadjuvant chemotherapy. DENND2D expression was evaluated by immunohistochemistry in 181 stag...
Autores principales: | Ma, Wen-juan, Chen, Yukun, Peng, Jian-hong, Tang, Chaoming, Zhang, Ling, Liu, Min, Hu, Shanshan, Xu, Haineng, Tan, Hua, Gu, Yangkui, Pan, Zhi-zhong, Chen, Gong, Zhou, Zhong-guo, Zhang, Rong-xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076603/ https://www.ncbi.nlm.nih.gov/pubmed/35523764 http://dx.doi.org/10.1038/s41419-022-04885-8 |
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