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Regulation of A-to-I RNA editing and stop codon recoding to control selenoprotein expression during skeletal myogenesis
Selenoprotein N (SELENON), a selenocysteine (Sec)-containing protein with high reductive activity, maintains redox homeostasis, thereby contributing to skeletal muscle differentiation and function. Loss-of-function mutations in SELENON cause severe neuromuscular disorders. In the early-to-middle sta...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076623/ https://www.ncbi.nlm.nih.gov/pubmed/35523818 http://dx.doi.org/10.1038/s41467-022-30181-2 |