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Irisin protects cardiomyocytes against hypoxia/reoxygenation injury via attenuating AMPK mediated endoplasmic reticulum stress

Endoplasmic reticulum (ER) stress plays a central role in myocardial ischemia/reperfusion (I/R) injury. Irisin has been reported to have protective properties in ischemia disease. In this study, we aimed at investigating whether irisin could alleviate myocardial I/R injury by ER stress attenuation....

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Detalles Bibliográficos
Autores principales: Yue, Rongchuan, Lv, Mingming, Lan, Meide, Zheng, Zaiyong, Tan, Xin, Zhao, Xuemei, Zhang, Yulong, Pu, Jun, Xu, Lei, Hu, Houxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076689/
https://www.ncbi.nlm.nih.gov/pubmed/35523819
http://dx.doi.org/10.1038/s41598-022-11343-0