Mucosal-associated invariant T cells are associated with insulin resistance in childhood obesity, and disrupt insulin signalling via IL-17

AIMS/HYPOTHESIS: Mucosal-associated invariant T cells (MAIT cells) are an abundant population of innate T cells. When activated, MAIT cells rapidly produce a range of cytokines, including IFNγ, TNF-α and IL-17. Several studies have implicated MAIT cells in the development of metabolic dysfunction, b...

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Autores principales: Bergin, Ronan, Kinlen, David, Kedia-Mehta, Nidhi, Hayes, Eadaoin, Cassidy, Féaron C., Cody, Declan, O’Shea, Donal, Hogan, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076704/
https://www.ncbi.nlm.nih.gov/pubmed/35305128
http://dx.doi.org/10.1007/s00125-022-05682-w

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