Biological activity and interaction mechanism of the diketopiperazine derivatives as tubulin polymerization inhibitors

Microtubules are a favorable target for development of anticancer agents. In this study, the anti-proliferative activities of plinabulin and six diketopiperazine derivatives were evaluated against human lung cancer cell line NCI-H460 and human pancreatic cancer cell line BxPC-3. The inhibition activ...

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Detalles Bibliográficos
Autores principales: Tian, Zhenhua, Chu, Yanyan, Wang, Hui, Zhong, Lili, Deng, Mengyan, Li, Wenbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076956/
https://www.ncbi.nlm.nih.gov/pubmed/35538960
http://dx.doi.org/10.1039/c7ra12173c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076956/
https://www.ncbi.nlm.nih.gov/pubmed/35538960
http://dx.doi.org/10.1039/c7ra12173c

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